Statistical Design and Analysis of Clinical Trials: Principles and Methods (Chapman & Hall/CRC Biostatistics Series)
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Statistical Design and Analysis of Clinical Trials: Principles and ...
Book Title: Statistical Design and Analysis of Clinical Trials: Principles and Methods
Author: Shih, Weichung Joe
Brand: Taylor & Francis Ltd
Edition: 1
Binding: Hardcover
Number Of Pages: 244
Release Date: 03-08-2015
EAN: 9781482250497
Package Dimensions: 9.1 x 6.6 x 1.1 inches
Languages: English
Details:
Statistical Design and Analysis of Clinical Trials: Principles and Methods focuses on the biostatistics component of clinical trials, developed from the author's extensive experience teaching public health and medical students. This comprehensive text integrates scientific principles and statistical methods essential for designing, monitoring, and analyzing clinical trials.
The book covers key concepts such as ethical and safety principles, core trial design, sample size and power calculation, and statistical analysis techniques. It explores advanced topics including sequential designs for Phase II and III cancer trials, safety and efficacy monitoring, adaptive group sequential procedures, and handling missing data through multiple imputations.
Designed for students in biostatistics, epidemiology, medicine, pharmacy, and public health, this text equips them with the necessary tools to become effective clinical trial investigators.
