Cluster Randomised Trials (Chapman & Hall/CRC Biostatistics Series)
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Cluster Randomised Trials (Chapman & Hall/CRC Biostatistics Ser...
Book Details
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Publisher: Taylor & Francis Ltd
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Author: Richard J. Hayes
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Language: English
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Edition: 1st Edition
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ISBN: 9781584888161
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Pages: 338
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Cover: Hardcover, Import
About The Book
Cluster Randomised Trials by Richard J. Hayes, published by Taylor & Francis in 2009, offers an in-depth exploration of the design, conduct, and analysis of health trials where groups of individuals are randomly assigned to different treatments. This comprehensive book provides valuable insights into the advantages of cluster randomization, especially in evaluating interventions against infectious diseases, and emphasizes methods that balance rigor with practical application.
The book begins by introducing the core concepts behind cluster randomization, such as direct, indirect, and total effects. Hayes explores various design issues in cluster randomised trials (CRTs), including strategies to minimize contamination, use of stratification and restricted randomization to improve balance, and methods for calculating sample sizes. The book also addresses alternatives to basic two-arm CRTs, providing readers with a broader toolkit for trial design.
The second part of the book focuses on analytical methods, particularly regression techniques used for CRTs, and expands into important ethical considerations, trial monitoring, interim analyses, reporting, and interpretation. With practical examples drawn from real research studies, Hayes bridges the gap between theory and practical application, making complex statistical methods accessible to a wide audience.
Although primarily aimed at the medical and public health sectors, the rigorous methods and practical advice provided in Cluster Randomised Trials have applications in many other fields where large group data and interventions are used. This book is an essential resource for those planning, conducting, or analyzing cluster randomised trials, as well as for researchers and students in related disciplines.
