PRINCIPLES OF MOLECULAR ONCOLOGY 2ED (HB)

Author: BRONCHUD M.H.

Brand: Humana

Edition: 2

Binding: Hardcover

Number Of Pages: 736

Release Date: 01-12-2003

Details: Product Description


This complete updating and expansion of a highly praised survey of the molecular basis of cancer reflects emerging knowledge coming from genomics, proteomics, chemoprevention strategies, new molecular targets, therapeutic monoclonal antibodies, and innovative cytotoxic and cytostatic small molecular weight compounds. New topics of special interest include the combining of molecular diagnostics (expression profiling of genes and proteins) with developmental therapeutics and the "binary state" concept (active/inactive) that seeks more relevant targets within the global molecular matrix of a given cancer. The book looks forward to new strategies that will not just attempt to "kill" cancer cells and "cure" cancers forever, but to hit those molecular targets to reduce the proliferative advantage of cancer cells and abolish or diminish their metastatic properties.


Review


this is an excellent book that brings together leading experts in the field who have done a superb job of succinctly describing the advances in the basic sciences over the last few years and in showing how these advances have translated into improvements in cancer care. This book will be useful to anyone who studies cancer biology or takes care of cancer patients. - Doody's Health Sciences Book Review Journal From the foreword: Principles of Molecular Oncology provides valuable information for the continuing education of all oncologists. - Derek Crowther, PhD, MB BChir, FRCP, FRCR, University of Manchester and Christie Cancer Center, Manchester, UK Reviews of the First Edition: All the aspects of this complex and rapidly moving field are covered in this excellent book. Clinical oncologists will find a series of balanced reviews of the current state-of-the-art of the diagnosis and treatment of cancer based on molecular technology, and since cancer touches almost every field of clinical practice, specialists in other disciplines will find a very lucid and readable account of what is happening in one of the genuine success stories of molecular medicine. From the foreword by Sir David Weatherall, FRS, Institute of Molecular Medicine, Oxford University, UK Principles of Molecular Oncology provides a bold new look at the evolution of our knowledge of cancer. Authors from many disciplines are bringing together the facets that provide a comprehensive view of the whole...The reader will enjoy the opportunity to pause and look at the whole field as it stands today. The book will be both informative and intellectually stimulating. From the foreword by E. Donnall Thomas, MD, Fred Hutchinson Cancer Research Center and Nobel Laureate in Medicine/Physiology, 1990 This book is a broad yet comprehensive synopsis of the emerging field of molecular oncology...A detailed framework of the molecular basis of cancer and the potential utility in both diagnosis and treatment is presented. One area covered particularly well is apoptosis, with an emphasis on the clinical relevance of modulating this pathway in human neoplasia. In summary, this text is a nice presentation of the varied pathways that are disrupted in a cancer cell and suggestions of potential clinically useful targets for therapeutic intervention...This is a welcome addition to a clinician's library, facilely read from cover to cover. - Doody's Health Sciences Book Review Journal Practicing physicians and advanced medical students as well as biochemists molecular biologists, and geneticists involved in the identification of molecular markers, therapeutic targets , and the underlying basis of cancer will all benefit from the addition of Principles of Molecular Oncology to their bookshelves. - The Lancet

EAN: 9781588292797

Package Dimensions: 10.5 x 7.1 x 1.6 inches

Languages: English