Hyaluronan in Cancer Biology

Book Details

• Publisher: Academic Press

• Author: Robert Stern

• Language: English

• ISBN: 9780123741783

• Binding: Hardcover

• Edition: 1st

• Release Date: 23-04-2009

• Pages: 468

• Package Dimensions: 9.1 x 6.1 x 1.1 inches

• Format: Illustrated

About the Book

"Hyaluronan Biology and Cancer" by Robert Stern offers a comprehensive exploration into the fascinating and crucial relationship between hyaluronan (HA) and cancer progression. Recognized as an important regulator of cancer, hyaluronan's dual role—both supporting and hindering cancer metastasis—forms the core of this in-depth study.

Key Features:

• Comprehensive Coverage: This book provides cutting-edge insights into hyaluronan biology, focusing on HA receptors, hyaluronidases (enzymes that degrade HA), and HA synthesis enzymes, and how they relate to cancer biology.

• Role of Hyaluronan in Cancer: Hyaluronan plays a critical role in opening tissue spaces, aiding cancer cell motility, and supporting metastasis. The book also links cancer to wound healing, comparing cancer progression to a wound that fails to heal.

• Tumor Cell Mechanisms: Chapters delve into how hyaluronan influences tumor cell activation, proliferation, drug resistance, and other mechanisms driving cancer progression.

• Leading Expert Contributions: Written by international experts, the chapters draw from the latest research in hyaluronan in cancer initiation, progression, and dissemination, providing state-of-the-art information from top laboratories.

• Clinical Relevance: With its focus on understanding the molecular pathways involved in cancer biology, this book offers invaluable insights for researchers, clinicians, and those working in oncology and biomedical sciences.

"Hyaluronan Biology and Cancer" is essential reading for those studying cancer research, molecular biology, and biochemistry, as well as anyone interested in the complex role of extracellular matrix components in disease progression.