Guidebook to Molecular Chaperones and Protein-Folding Catalysts

Author: UNKNOWN

Brand: OUP Oxford

Binding: Paperback

Number Of Pages: 580

Release Date: 27-11-1997

Part Number: illustrations

Details: Product Description


The precise shape of a protein is a crucial factor in its function. How do proteins become folded into the right conformation? Molecular chaperones and protein folding catalysts bind to developing polypeptides in the cytoplasm and ensure correct folding and transport. This Guidebook catalogues the latest information on nearly 200 of these molecules, including the important class of heat shock proteins; each entry is written by leading researchers in the field.


Review


This book describes important aspects of the structure, function, and regulation of all known chaperones and enzymes involved in protein folding. The information is up-to-date and the text is arranged in a concise and easy to read format. This is a useful handbook, not only for scientists in the protein folding field, but also for those working in related areas for whom the comprehensive summaries will be especially valuable. 4 Stars. --
Doody's Journal

The book is divided into 17 parts, with the first 15 cataloguing the different classes of molecular chaperones. Information on nearly 200 chaperones have been included. Each part contains a brief entry, typically between one to three pages in length, of each family member. In the literature, many chaperones are referred to by more than one name, and a particularly useful feature in the book is the listing of these alternative names. Other information includes isolation, gene sequence, biological activities, regulation, biological interactions and mutagenesis studies. . . . [T]he book is a must for everyone working in the field of molecular chaperones. In addition, since protein folding is an integral part of the general field of protein science, it will also be invaluable to anyone interested in that field. The book should be on the shelf of every library housing biologically and biochemically relevant literature.--
The Quarterly Review of Biology




About the Author


Dr Mary-Jane Gething (Partner in the Sambrook & Tooze Partnership, our co-publishers of the Guidebooks Series) Dept of Biochemistry, Melbourne University, Parkville 3052, Australia. Tel: 00 61 3 9344 5948. Fax: 00613 9347 9109. Email: gething@ariel.ucs.unimelb.edu.au

EAN: 9780198599487

Package Dimensions: 9.5 x 7.3 x 1.3 inches

Languages: English